Low AMH. High FSH. Fewer eggs than expected during IVF. At some point, your doctor may have brought up donor eggs as the next logical move.
That conversation is hard. And many women who have it are not yet ready to close the door on their own eggs.
Ovarian PRP—also referred to as "PRP Ovarian Rejuvenation"—is a procedure that has helped some of those women. Not all of them. But enough that it is worth knowing whether you are a candidate before you decide anything else.
At Kiran Infertility Center Delhi, we do this procedure regularly for women with diminished ovarian reserve, poor IVF response, and premature ovarian insufficiency. This page covers what the treatment actually involves, who it tends to work for, what the results look like, and what it costs.
Think of blood the way a lab technician does. It is not one uniform liquid. Spin it in a tube and it separates. The heavy red cells sink to the bottom. Above that sits a thin band called the buffy coat. And floating at the top is plasma—pale yellow, mostly water, carrying dissolved proteins your body depends on.
Among those proteins are growth factors. These are the same signals your body sends when something is torn or bruised. A scraped knee, a strained tendon, inflamed tissue—the moment injury happens, platelets at the site release these compounds to start the repair process. The body has been using this system for its entire existence. PRP borrows it.
To make PRP, a blood draw — roughly the same volume as a standard liver function test — is spun at high speed in a centrifuge. That spinning concentrates the platelet layer until it holds several times more platelets per milliliter than ordinary circulating blood. The specific growth factors it carries include VEGF, PDGF, TGF-beta, and EGF, each with a different role in stimulating tissue activity.
"When that concentrated solution is injected into the ovary, those signals reach the follicular tissue that has gone quiet. Some follicles stop developing not because they are gone, but because the local environment stopped supporting them."
The material is yours from start to finish. Nothing is added from outside. In medical terminology, a procedure that uses only the patient's own biological material is called autologous. That distinction matters because it is also why the side effect profile is so low.
Also known as: Ovarian Rejuvenation Therapy | PRP Ovarian Rejuvenation
This treatment targets a specific problem: ovaries that are not producing eggs well. Age alone is not the deciding factor — your blood tests and ultrasound findings tell us more than your birth year does.
We run a specific set of blood tests before anything else gets scheduled. AMH tells us how much ovarian reserve is left. Day 2 or Day 3, FSH and LH give us a picture of how hard the brain is working to push the ovaries. Estradiol and prolactin fill in the hormonal context. Alongside those, a transvaginal ultrasound counts the antral follicles—small resting follicles visible on the scan that indicate how many eggs may still be available.
On the day of your procedure, we draw roughly 10 to 20 mL of blood from your arm. The sample goes into a centrifuge immediately. After spinning at a set speed for a set duration, the blood separates into distinct layers. We pull out the platelet-rich layer, which is now several times more concentrated than what flows naturally in your veins. The quality of this step matters enormously.
A fine needle is guided transvaginally under real-time ultrasound imaging and advanced into the cortex of each ovary. The ultrasound view allows the doctor to see exactly where the needle tip is at every moment. The PRP is deposited at specific sites within the ovarian tissue where the growth factor release will have the most impact. You are kept comfortable with local anesthesia or light sedation.
Plan for a few hours at the clinic that day. We keep you with us for roughly an hour afterwards to make sure you are comfortable and that there is no unexpected cramping or dizziness before you leave. Most women feel well enough to drive themselves home. Heavy exercise is restricted for two to three days, but desk work is fine by the following morning.
The first check-in is at four weeks. We draw blood for AMH and FSH and do a quick ultrasound to count the antral follicles. The second appointment falls between weeks eight and twelve. This combined picture tells us clearly how your ovaries have responded to treatment and what the next step looks like from there.
The clinical evidence for ovarian PRP is still accumulating. But the studies that exist consistently point in the same direction for women with poor ovarian reserve:
PRP does not reverse severe or end-stage ovarian failure. If your AMH is at zero and no follicular activity shows on ultrasound, the response to PRP is unlikely to be meaningful. The results above apply to women who still have some residual ovarian activity.
The cost depends on practical variables: number of sessions, combination with IVF, sedation type, and required pre-procedure tests.
Per Session (Indicative Price)
At Kiran Infertility Center, Delhi, we give you the full cost breakdown at your first consultation, before anything is scheduled. The number you see then is the number you pay. No surprise additions at the end.
Using your own blood means no immune reaction, no rejection, and no risk of allergic response. From a biological standpoint, this is one of the lowest-risk interventions in fertility medicine.
Normal Temporary Discomfort:
Schedule a private consultation with our experts in Delhi. Our team will examine your medical history and present all available options while developing a custom treatment plan with complete cost transparency.
A-15, First Floor, Greater Kailash, New Delhi - 110048 | Mon-Sat 10:00 AM - 6:00 PM
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