Best Pre-implantation Genetic Screening in Delhi for Healthy Pregnancies

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Pre-implantation genetic screening or PGS represents one of the most important breakthroughs which has emerged during modern times in the field of reproductive medicine.

The fertility doctors at Kiran Infertility Center in Delhi use this technique to evaluate the genetic health of every embryo which they will implant in order to give couples their best opportunity for a successful pregnancy.

Our clinical experience which exceeds 30 years combined with our treatment of over 30000 couples demonstrates that Pre-implantation Genetic Screening improves reproductive outcomes for patients who have known genetic disorders or who have repeated IVF failures or ongoing miscarriages.

Our board-certified fertility specialists together with embryologists work according to ESHRE guidelines which follow international standards of patient care to deliver scientific excellence and compassionate treatment to each patient.

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What Is Genetic Screening in IVF and Why Does It Matter?

The procedure of genetic screening during an IVF cycle involves testing embryos to detect both chromosomal defects and genetic disorders which can be inherited before the transfer of embryos. Genetic screening enables our fertility specialists and embryologists to make data-driven choices about embryo selection because it provides them with evidence which helps them to choose embryos that will most likely succeed in implanting and developing into healthy infants.

Research in reproductive medicine indicates that approximately 50 to 70 percent of human embryos exhibit chromosomal abnormalities which increase with maternal age. The majority of IVF implantation failures and early miscarriages occur because of these abnormalities. Genetic screening helps solve this important problem which makes it one of the most effective tools used in modern fertility treatment today.

💡 Clinical Insight

In our clinical experience at KIC Delhi, patients who undergo PGS before embryo transfer show a significantly lower rate of early pregnancy loss compared to those who transfer unscreened embryos — particularly women over 35 and those with previous IVF failures.

Two Primary Testing Methods

PGS / PGT-A

Examines all 24 chromosomes for each embryo to identify aneuploidies, the main reason for IVF failure and miscarriage.

PGD / PGT-M

Examines specific single-gene mutations which both parents pass to their child, focusing on inherited disorders.

What Is Pre-implantation Genetic Diagnosis (PGD)? A Clinical Overview

Pre-implantation Genetic Diagnosis (PGD) enables couples to evaluate their genetic compatibility through testing. PGT-M (Preimplantation Genetic Testing for Monogenic Disorders) enables doctors to detect specific genetic mutations in embryos before transfer to the uterus.

When Is PGD Medically Indicated?

  • Carrier status for autosomal recessive disorders (Thalassemia, Cystic Fibrosis).
  • Autosomal dominant disorders (Huntington's, Marfan syndrome, BRCA1/BRCA2).
  • X-linked genetic disorders (Duchenne muscular dystrophy, Haemophilia A/B).
  • Previous child diagnosed with a severe single-gene disorder.
  • Balanced chromosomal translocation or inversion.

Precision Medicine Approach

PGD functions as a precision medicine test which healthcare providers develop for each couple based on their unique genetic mutations. Before the IVF cycle begins, our genetic team designs and validates a custom molecular probe targeting that specific mutation.

The workup period establishes a preparatory phase which lasts 4 to 8 weeks because it represents the only time a couple can go through one specific mutation process.

Pre-implantation Genetic Testing – Our Clinical Process at KIC Delhi

Following international standards through an established clinical pathway.

Step 1
Assessment

Thorough consultation reviewing medical records, IVF results, and family genetic information.

Step 2
Stimulation

Customized ovarian stimulation and egg retrieval via a 20-30 minute day-care procedure.

Step 3
Fertilization

ICSI fertilization and blastocyst culture in ISO-standard embryology incubators (5-6 days).

Step 4: Blastocyst Biopsy
Precision Biopsy

Our senior embryologists extract 5 to 8 cells from the outer cell layer (trophectoderm). The inner cell mass remains untouched. Technical Standard: At KIC, only trained embryologists with advanced micromanipulation skills conduct biopsies. We prioritize Day 5/6 biopsies for maximum accuracy and embryo safety.

Step 5
Analysis

Next Generation Sequencing (NGS) examines 24 chromosomes with >98% accuracy.

Step 6
FET Transfer

Selection of chromosomally normal embryos for transfer during a Frozen Embryo Transfer cycle.

Step 7
Monitoring

Beta-hCG blood test (12-14 days post-transfer) followed by standard obstetric prenatal care.

PGS Testing Cost in Delhi – Transparent Pricing

Indicative PGS Cost

Rs. 40,000 – 80,000

For genetic analysis of up to 5 to 8 embryos (in addition to base IVF cycle cost).

  • ✓ NGS-based precision testing
  • ✓ Biopsy & Trophectoderm analysis
  • ✓ Pre- and post-testing counselling

Cost Factors

Embryo Count: Laboratory expenses increase with each embryo analyzed.
NGS Method: We use gold-standard NGS over outdated FISH methods.
Vitrification: Includes charges for flash-freezing and annual storage.

PGD Testing Cost in Delhi – What Couples Should Know

Cost Element Indicative Price Range
Genetic Workup & Probe Design Rs. 25,000 – Rs. 50,000 (per mutation)
PGT-M Analysis (Single-Gene) Rs. 50,000 – Rs. 80,000
Combined PGD + PGS (PGT-M + PGT-A) Rs. 80,000 – Rs. 1,50,000

Financial Transparency Promise: Every patient receives a detailed written cost estimate. KIC provides multiple EMI payment options and assistance with insurance pre-authorization.

Is Pre-implantation Genetic Screening Right for You?

🔍 PGS (PGT-A) Benefits

  • Advanced Maternal Age: Significant benefit for women over 35 to 42.
  • Recurrent Pregnancy Loss: Detecting chromosomal abnormalities.
  • Repeated IVF Failure: For patients with 2+ unsuccessful attempts.
  • Semen Parameter Deficiencies: Addressing DNA fragmentation.

🧬 PGD (PGT-M) Benefits

  • Recessive Gene Carriers: For parents sharing the same recessive gene.
  • Dominant Gene Carriers: Mutations like Huntington's or BRCA1/2.
  • X-linked Diseases: Preventing Haemophilia or Duchenne dystrophy.
  • Hereditary Cancers: Screening for Lynch syndrome or BRCA.

Why Trust Kiran Infertility Center for Genetic Screening?

🏆
Track Record

Leading advanced fertility treatments since the 1990s as a pioneer in PGS testing.

🔬
Technology

ISO-Standard labs using ESHRE-aligned Next Generation Sequencing (NGS) protocols.

🌍
Global Trust

Serving patients from across India, the Middle East, and Africa with dedicated case management.

Our Medical Team

Find Out If Genetic Screening Is Right For You

Get a clear answer based on your specific clinical needs. We offer free genetic counselling and transparent written cost estimates.

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A-15, First Floor, Greater Kailash, New Delhi | Mon - Sat: 10:00 AM to 6:00 PM

Frequently Asked Questions About Pre-Implantation Genetic Screening

Click on a question to view the answer regarding PGS Testing.

Take the Most Informed Step Toward a Healthy Pregnancy

Please schedule a private consultation with our Pre-implantation Genetic Screening experts at Kiran Infertility Center in Delhi. Our team will examine your medical history and present all available options to you while developing a custom treatment plan which includes complete cost information from the beginning of our consultation.

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Our specialists are here to guide you with compassion, expertise, and personalized care every step of the way.

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